Rating Change
HC Wainwright & Co. analysts downgraded Karyopharm Therapeutics Inc. (NASDAQ:KPTI) from Buy to Neutral on July 31, 2026.
Rating Change HC Wainwright & Co. analysts downgraded Karyopharm Therapeutics Inc. (NASDAQ:KPTI) from Buy to Neutral on July 31, 2026.

HC Wainwright & Co. analysts downgraded Karyopharm Therapeutics Inc. (NASDAQ:KPTI) from Buy to Neutral on July 31, 2026.
Karyopharm Therapeutics Inc. operates in the Healthcare sector. The stock currently trades at $1.92 with a market capitalization of $59.5M.
Analyst downgrades can weigh on a stock in the short term as institutional investors who follow HC Wainwright & Co.'s research adjust their positions. However, downgrades also sometimes create buying opportunities if the market overreacts to the rating change. The reasoning behind the downgrade matters more than the rating itself.
Analyst ratings and price targets are one input among many for investment decisions. Historical studies show that consensus analyst recommendations have mixed predictive power on their own, but significant changes in consensus — such as multiple upgrades or downgrades in a short period — can be more meaningful signals.
Among the 10 most recent ratings: 9 Buy, 1 Hold, 0 Sell.
| Date | Firm | Rating | Price Target |
|---|---|---|---|
| Jul 31, 2026 | Piper Sandler | Overweight | N/A |
| Jul 31, 2026 | HC Wainwright & Co. | Neutral | N/A |
| May 06, 2026 | HC Wainwright & Co. | Buy | N/A |
| Apr 27, 2026 | Piper Sandler | Overweight | N/A |
| Mar 30, 2026 | Piper Sandler | Overweight | N/A |
Related Tools: Analyst Ratings Dashboard | View KPTI Stock Page
A Neutral rating from HC Wainwright & Co. reflects the analyst's outlook on Karyopharm Therapeutics Inc. (NASDAQ:KPTI). Analyst ratings are one factor investors consider alongside earnings, valuation, and sector trends.
Browse recent upgrades and downgrades on our Analyst Ratings Dashboard or the KPTI forecast page.
Current market data
NASDAQ · KPTI
$1.85
Down: -$0.21 · -10.19%
Live quote updated
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