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Smart Investors Daily
SP

NASDAQ · SPRO

Spero Therapeutics, Inc.

Healthcare · Biotechnology

$1.22

Up+$0.01 (+0.83%)

Updated Aug 23, 2026, 3:47 PM

SID Score

3.2/10

Composite research score

Smart Money

Institutional and insider signal

Market cap
132.38M
P/E ratio
-3.02
Dividend yield
0.00%
52-week range
$1.08 – $3.08
Volume
359.14K
Avg. volume
638.96K

Price performance

SPRO price history

1M range · 20 trading sessions · Daily adjusted prices

SPRO closed at $1.22 after 20 trading sessions, up 3.39% for the selected period.

Last close
$1.22
Period change
+3.39%
Period low
$1.15
Period high
$1.27
Daily close
View OHLC price history
SPRO OHLC price history, latest 40 sessions
DateOpenHighLowCloseVolume
Aug 21, 2026$1.22$1.2462$1.21$1.22359.14K
Aug 20, 2026$1.22$1.27$1.20$1.21558.77K
Aug 19, 2026$1.20$1.24$1.192$1.23480.18K
Aug 18, 2026$1.20$1.20$1.175$1.20477.41K
Aug 17, 2026$1.21$1.24$1.19$1.19299.01K
Aug 14, 2026$1.26$1.26$1.1937$1.23744.55K
Aug 13, 2026$1.26$1.30$1.21$1.241.29M
Aug 12, 2026$1.24$1.245$1.185$1.19774.55K
Aug 11, 2026$1.24$1.25$1.21$1.23364.06K
Aug 10, 2026$1.25$1.276$1.225$1.23351.02K
Aug 7, 2026$1.27$1.2795$1.24$1.26459.03K
Aug 6, 2026$1.26$1.275$1.23$1.27974.68K
Aug 5, 2026$1.25$1.28$1.21$1.26574.91K
Aug 4, 2026$1.15$1.25$1.15$1.23752.11K
Aug 3, 2026$1.19$1.22$1.125$1.151.37M
Jul 31, 2026$1.20$1.2138$1.17$1.17824.58K
Jul 30, 2026$1.20$1.22$1.175$1.20487.67K
Jul 29, 2026$1.20$1.21$1.16$1.191.06M
Jul 28, 2026$1.18$1.28$1.15$1.1951.6M
Jul 27, 2026$1.20$1.2299$1.16$1.181.35M

Latest SPRO news

The latest Smart Investors Daily articles mentioning SPRO.

SPRO research

Overview

Company profile and research snapshot.

Company profile

Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. Besides, it is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.

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Analyst outlook

Consensus and target data currently published for this company.

Consensus
Average target
Implied upside
Analysts
SPRO recent ratings
DateFirmRatingTarget
Jan 30, 2025HC Wainwright & Co.Buy
Dec 20, 2024Evercore ISI GroupIn-Line
Dec 2, 2024HC Wainwright & Co.Buy
Nov 18, 2024TD CowenHold
Nov 15, 2024Cantor FitzgeraldOverweight
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News briefing

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AI research layers

Interpretive context generated from the platform’s current data sources.

No results

AI research layers have not been published yet.