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Smart Investors Daily
SP

NASDAQ · SPRO

Spero Therapeutics, Inc.

Healthcare · Biotechnology

$1.17

Down-$0.02 (-1.68%)

Updated Oct 8, 2026, 4:55 AM

SID Score

3.0/10

Composite research score

Smart Money

—

Institutional and insider signal

Market cap
132.38M
P/E ratio
-3.02
Dividend yield
0.00%
52-week range
$1.08 – $3.08
Volume
236.67K
Avg. volume
638.96K

Price performance · SPRO

SPRO price history

1M range · 21 trading sessions · Daily adjusted prices

Prices through Oct 7, 2026

SPRO closed at $1.17 after 21 trading sessions, up 0.00% for the selected period.

Last close
$1.17
Period change
+0.00%
Period low
$1.11
Period high
$1.36
Daily close
View OHLC price history
SPRO OHLC price history, latest 40 sessions
DateOpenHighLowCloseVolume
Oct 7, 2026$1.19$1.19$1.16$1.17236.67K
Oct 6, 2026$1.21$1.236$1.18$1.19347.57K
Oct 5, 2026$1.17$1.20$1.15$1.16942.72K
Oct 2, 2026$1.26$1.266$1.1705$1.19906.92K
Oct 1, 2026$1.22$1.31$1.195$1.261.04M
Sep 30, 2026$1.21$1.29$1.20$1.21558.21K
Sep 29, 2026$1.20$1.22$1.17$1.20334.91K
Sep 28, 2026$1.22$1.22$1.175$1.19393.26K
Sep 25, 2026$1.27$1.29$1.21$1.23542.77K
Sep 24, 2026$1.25$1.29$1.24$1.25476.93K
Sep 23, 2026$1.36$1.3977$1.24$1.261.4M
Sep 22, 2026$1.30$1.44$1.28$1.367.76M
Sep 21, 2026$1.14$1.15$1.12$1.14319.1K
Sep 18, 2026$1.12$1.21$1.115$1.13501.37K
Sep 17, 2026$1.14$1.14$1.114$1.12181.77K
Sep 16, 2026$1.12$1.14$1.10$1.11439.64K
Sep 15, 2026$1.14$1.151$1.11$1.13225.28K
Sep 14, 2026$1.13$1.16$1.13$1.14267.14K
Sep 11, 2026$1.13$1.15$1.13$1.13310.63K
Sep 10, 2026$1.18$1.18$1.12$1.12569.29K
Sep 9, 2026$1.20$1.21$1.17$1.17367.06K

Latest SPRO news

The latest Smart Investors Daily articles mentioning SPRO.

SPRO research

Overview

Company profile and research snapshot.

Company profile

Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. Besides, it is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.

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Analyst outlook

Consensus and target data currently published for this company.

Consensus
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Average target
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Implied upside
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Analysts
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SPRO recent ratings
DateFirmRatingTarget
Sep 14, 2026HC Wainwright & Co.Buy—
Jan 30, 2025HC Wainwright & Co.Buy—
Dec 20, 2024Evercore ISI GroupIn-Line—
Dec 2, 2024HC Wainwright & Co.Buy—
Nov 18, 2024TD CowenHold—
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News briefing

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AI research layers

Interpretive context generated from the platform’s current data sources.

No results

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