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Smart Investors Daily
SP

NASDAQ · SPRO

Spero Therapeutics, Inc.

Healthcare · Biotechnology

$1.13

Up+$0.01 (+0.89%)

Updated Sep 13, 2026, 9:08 PM

SID Score

2.9/10

Composite research score

Smart Money

Institutional and insider signal

Market cap
132.38M
P/E ratio
-3.02
Dividend yield
0.00%
52-week range
$1.08 – $3.08
Volume
310.63K
Avg. volume
638.96K

Price performance

SPRO price history

1M range · 19 trading sessions · Daily adjusted prices

SPRO closed at $1.13 after 19 trading sessions, down 5.04% for the selected period.

Last close
$1.13
Period change
-5.04%
Period low
$1.12
Period high
$1.23
Daily close
View OHLC price history
SPRO OHLC price history, latest 40 sessions
DateOpenHighLowCloseVolume
Sep 11, 2026$1.13$1.15$1.13$1.13310.63K
Sep 10, 2026$1.18$1.18$1.12$1.12569.29K
Sep 9, 2026$1.20$1.21$1.17$1.17367.06K
Sep 8, 2026$1.21$1.22$1.19$1.19348.59K
Sep 4, 2026$1.20$1.22$1.185$1.21362.98K
Sep 3, 2026$1.22$1.23$1.2008$1.22203.33K
Sep 2, 2026$1.20$1.2388$1.20$1.22169.51K
Sep 1, 2026$1.22$1.22$1.18$1.20385.4K
Aug 31, 2026$1.20$1.23$1.20$1.22338.47K
Aug 28, 2026$1.21$1.22$1.1808$1.20312.83K
Aug 27, 2026$1.22$1.23$1.18$1.21538.49K
Aug 26, 2026$1.22$1.228$1.20$1.22154.76K
Aug 25, 2026$1.23$1.26$1.20$1.23645.54K
Aug 24, 2026$1.22$1.24$1.20$1.215367.27K
Aug 21, 2026$1.22$1.2462$1.21$1.22359.14K
Aug 20, 2026$1.22$1.27$1.20$1.21558.77K
Aug 19, 2026$1.20$1.24$1.192$1.23480.18K
Aug 18, 2026$1.20$1.20$1.175$1.20477.41K
Aug 17, 2026$1.21$1.24$1.19$1.19299.01K

Latest SPRO news

The latest Smart Investors Daily articles mentioning SPRO.

SPRO research

Overview

Company profile and research snapshot.

Company profile

Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. Besides, it is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.

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Analyst outlook

Consensus and target data currently published for this company.

Consensus
Average target
Implied upside
Analysts
SPRO recent ratings
DateFirmRatingTarget
Jan 30, 2025HC Wainwright & Co.Buy
Dec 20, 2024Evercore ISI GroupIn-Line
Dec 2, 2024HC Wainwright & Co.Buy
Nov 18, 2024TD CowenHold
Nov 15, 2024Cantor FitzgeraldOverweight
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News briefing

No generated briefing is available yet.

AI research layers

Interpretive context generated from the platform’s current data sources.

No results

AI research layers have not been published yet.