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NASDAQ · AZN

AstraZeneca PLC

Healthcare · Drug Manufacturers - General

$159.20

Up+$0.42 (+0.26%)

Updated Oct 11, 2026, 1:10 PM

SID Score

6.7/10

Composite research score

Smart Money

59/100

Neutral

Market cap
279.95B
P/E ratio
33.06
Dividend yield
0.96%
52-week range
$80.48 – $212.71
Volume
2.12M
Avg. volume
5.47M

Price performance · AZN

AZN price history

1M range · 20 trading sessions · Daily adjusted prices

Prices through Oct 9, 2026

AZN closed at $159.20 after 20 trading sessions, down 2.80% for the selected period.

Last close
$159.20
Period change
-2.80%
Period low
$156.53
Period high
$168.37
Daily close
View OHLC price history
AZN OHLC price history, latest 40 sessions
DateOpenHighLowCloseVolume
Oct 9, 2026$159.45$160.065$158.53$159.202.12M
Oct 8, 2026$159.80$160.05$156.72$158.783.49M
Oct 7, 2026$159.12$161.29$158.53$160.122.46M
Oct 6, 2026$159.795$159.96$156.26$158.612.05M
Oct 5, 2026$156.76$157.20$154.81$156.532.26M
Oct 2, 2026$158.46$158.795$156.41$156.903.04M
Oct 1, 2026$160.77$161.325$157.54$157.703.38M
Sep 30, 2026$164.47$164.484$161.46$161.472.23M
Sep 29, 2026$165.09$166.465$163.24$164.213.37M
Sep 28, 2026$165.69$167.52$165.39$166.151.73M
Sep 25, 2026$166.16$166.81$164.60$166.582.07M
Sep 24, 2026$162.91$166.25$162.91$164.563.19M
Sep 23, 2026$166.58$167.59$163.33$163.332.36M
Sep 22, 2026$167.84$169.35$166.74$168.372.31M
Sep 21, 2026$168.45$169.00$167.11$168.102.94M
Sep 18, 2026$167.15$167.83$165.54$166.083.06M
Sep 17, 2026$164.59$166.29$164.295$166.143.81M
Sep 16, 2026$164.21$165.42$162.02$162.893.86M
Sep 15, 2026$161.42$163.90$160.71$161.852.94M
Sep 14, 2026$164.08$164.55$162.14$163.783.09M

Latest AZN news

The latest Smart Investors Daily articles mentioning AZN.

AZN research

Overview

Company profile and research snapshot.

Company profile

A merger between Astra of Sweden and Zeneca Group of the United Kingdom formed AstraZeneca in 1999. The firm sells branded drugs across a number of major therapeutic areas, including oncology (about 40% of total revenue), cardiovascular, renal, and metabolic (25%), rare disease (17%), and respiratory and immunology (15%). The majority of sales comes from international markets, with the United States representing close to one third of its sales.

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Analyst outlook

Consensus and target data currently published for this company.

Consensus
Buy
Average target
$102.67
Implied upside
—
Analysts
6
AZN recent ratings
DateFirmRatingTarget
Jul 13, 2026Berenberg BankBuy—
Jun 26, 2026DeutscheSell—
Jun 26, 2026JefferiesBuy—
Jun 11, 2026DeutscheSell—
Jun 9, 2026JefferiesBuy—
Open full forecast

News briefing

Generated Oct 10, 2026, 9:06 PM

Why Is AZN Up Today?

AstraZeneca gained a modest 0.26% today as the market digested multiple positive developments across its oncology pipeline and AI-driven drug discovery initiatives. The gains reflect investor optimism about the company's expanding portfolio and strategic partnerships, though sentiment remains measured across the sector.

    Bottom line: AstraZeneca's modest gains reflect incremental positive momentum from companion diagnostic approvals, AI-driven drug discovery investments, and an expanding oncology pipeline, though the market remains cautiously optimistic given sector-wide competitive and patent cliff pressures. Investors should monitor FDA decisions on the new lung cancer treatment and the successful commercialization of ETCAMAH in Europe as key catalysts that could validate the company's growth strategy.

    Yahoo · Oct 10, 2026

    AstraZeneca (LSE:AZN) Puts AI Into Biologics Labs With New Discovery Tie Up

    AstraZeneca (LSE:AZN) has launched a new AI-driven biologics discovery collaboration with Carterra, announced ahead of trading on 9 October 2026. The partnership links AstraZeneca's AI models with Carterra's high-throughput biosensor instruments to create autonomous, lab-in-the-loop discovery workflows. The project focuses on large molecule biologics, aiming to shorten experimental decision cycles and scale up antibody and protein engineering campaigns. This AI and Carterra lab-in-the-loop...

    Yahoo · Oct 8, 2026

    Guardant Health Announces Approval in Europe of Guardant360® CDx as Companion Diagnostic for AstraZeneca’s ETCAMAH™ (camizestrant) in Advanced ER-positive Breast Cancer

    PALO ALTO, Calif., October 08, 2026--Guardant Health, Inc. (Nasdaq: GH), a leading precision oncology company, today announced that Guardant360® CDx has received CE-marking under Europe’s in Vitro Diagnostic Medical Devices Regulation as a companion diagnostic (CDx) to identify patients with estrogen receptor (ER)-positive, HER2-negative locally advanced or metastatic breast cancer who may benefit from treatment with ETCAMAH™ (camizestrant), AstraZeneca’s next-generation oral selective estrogen

    Yahoo · Oct 8, 2026

    AstraZeneca (AZN) Seeks FDA Approval for New Lung Cancer Treatment. Can It Fuel Oncology Growth?

    AstraZeneca PLC (US) (NYSE:AZN) is on the cusp of unlocking a new growth engine in lung cancer treatment. On September 29, Reuters reported that the company has applied to the US Food and Drug Administration for approval of ORPATHYS-TAGRISSO. But can this potential lung cancer breakthrough meaningfully accelerate AstraZeneca’s broader oncology growth story, or will […]

    AI research layers

    Interpretive context generated from the platform’s current data sources.

    AstraZeneca PLC Stock Performance

    AstraZeneca PLC shares currently trade at $159.20, reflecting a modest decline of 0.28% over the past month and a more pronounced 6.06% pullback over three months, per SID market data. Despite near-term weakness, the stock has delivered a robust 85.4% gain over the trailing twelve months, significantly outperforming broader healthcare sector benchmarks. The stock is currently trading below both its 50-day moving average of $162.08 and its 200-day moving average of $168.91, indicating sustained downward pressure. The 14-day relative strength index stands at 31.4, approaching oversold territory and suggesting the selling momentum may be nearing exhaustion. AstraZeneca maintains a notably low beta of 0.168, according to Massive/Polygon data, underscoring its defensive characteristics relative to the broader market. Average daily volume stands at approximately 5.47 million shares, supporting adequate liquidity for institutional positioning.

    AstraZeneca PLC Valuation Analysis

    AstraZeneca PLC carries a market capitalization of approximately $279.9 billion, positioning it among the largest global pharmaceutical companies, per SID market data. The stock trades at a price-to-earnings ratio of 33.06, which commands a premium relative to the broader healthcare sector. The PEG ratio of 4.53, according to SEC filings and consensus growth estimates, suggests the current earnings multiple substantially exceeds the company's projected growth rate, indicating the stock may be richly valued on a growth-adjusted basis. AstraZeneca's price-to-book ratio stands at 6.24, reflecting significant intangible asset value associated with its pharmaceutical pipeline and intellectual property portfolio. The company offers a dividend yield of approximately 1.56%, providing modest income to shareholders. These valuation metrics collectively position AstraZeneca at a premium within its peer group, consistent with market expectations for continued pipeline-driven revenue expansion and oncology franchise growth.

    Smart Money Activity for AZN

    AstraZeneca PLC registers a smart money score of 59 with a neutral overall signal, per SID market data. The institutional component scores a perfect 25 out of 25, indicating maximum conviction from large asset managers and reflecting strong positioning among hedge funds and mutual funds in recent 13F institutional filings. Insider activity scores 12.5 out of 25, with SEC Form 4 filings revealing three insider transactions over the past 90 days — all purchases and zero sales. This unanimous buying pattern among corporate insiders suggests internal confidence in the company's forward outlook, even as the stock experiences near-term price weakness. Dark pool activity registers a relatively low score of 9.2 out of 25, indicating limited off-exchange institutional block trading in recent periods. Congressional trading activity scores 12 out of 25, reflecting moderate engagement from elected officials. The divergence between robust institutional holdings and subdued dark pool activity warrants monitoring as technical conditions evolve.

    AstraZeneca PLC Earnings Outlook

    AstraZeneca PLC delivered a significant earnings surprise in its most recent reported quarter, posting actual earnings of $2.63 per share against an analyst consensus estimate of $1.52, representing a $1.11 positive surprise, according to company earnings reports. This 73% beat underscores strong operational execution across the company's oncology and biopharmaceuticals portfolio. Looking ahead, analyst estimates project earnings of $1.44 per share for the upcoming July 2026 quarter, followed by estimates of $1.35 for both the October and November 2026 reporting periods, per consensus analyst estimates. The sequential decline in estimates from $1.44 to $1.35 may reflect anticipated seasonality or pipeline investment timing. With three forward quarters carrying pending results, the trajectory of analyst revisions will be critical in determining whether the substantial beat from the most recent quarter represents a sustainable inflection in profitability or a one-time outperformance driven by non-recurring factors.

    Wall Street Analyst Ratings for AZN

    Wall Street consensus on AstraZeneca PLC remains divided, with recent analyst actions reflecting contrasting views on the stock's risk-reward profile. Berenberg Bank reiterated a Buy rating on July 13, 2026, while Jefferies also maintained its Buy recommendation through multiple reiterations on June 9 and June 26, per Wall Street analyst reports. In contrast, Deutsche Bank has taken a bearish stance, reiterating a Sell rating on both June 11 and June 26, 2026, creating a notable divergence among major research desks. The split between bullish and bearish coverage highlights ongoing debate around AstraZeneca's premium valuation, with the P/E ratio of 33.06 serving as a key friction point, according to SID consensus data. Two of the three covering firms maintain Buy ratings, establishing a two-thirds majority bullish skew among recent actions. The frequency of reiterations from both Jefferies and Deutsche within a single month suggests heightened analytical attention amid recent share price weakness.