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Smart Investors Daily
CY

NASDAQ · CYCN

Cyclerion Therapeutics, Inc.

Healthcare · Biotechnology

$3.89

Down-$0.18 (-4.42%)

Updated Aug 23, 2026, 11:50 PM

SID Score

6.0/10

Composite research score

Smart Money

Institutional and insider signal

Market cap
5.57M
P/E ratio
-2.45
Dividend yield
0.00%
52-week range
$1.03 – $8.48
Volume
65.75K
Avg. volume
695.98K

Price performance

CYCN price history

1M range · 20 trading sessions · Daily adjusted prices

CYCN closed at $3.89 after 20 trading sessions, up 11.14% for the selected period.

Last close
$3.89
Period change
+11.14%
Period low
$3.44
Period high
$4.13
Daily close
View OHLC price history
CYCN OHLC price history, latest 40 sessions
DateOpenHighLowCloseVolume
Aug 21, 2026$4.07$4.2883$3.78$3.8965.75K
Aug 20, 2026$4.07$4.4682$4.0101$4.0786.13K
Aug 19, 2026$4.05$4.30$4.05$4.1314.6K
Aug 18, 2026$3.92$4.25$3.8704$4.1214.64K
Aug 17, 2026$3.76$4.20$3.76$4.0315.36K
Aug 14, 2026$3.85$3.9699$3.73$3.7924.21K
Aug 13, 2026$3.92$4.45$3.8072$3.9182.97K
Aug 12, 2026$3.53$4.16$3.53$3.92102.69K
Aug 11, 2026$3.56$3.67$3.40$3.5710.6K
Aug 10, 2026$3.51$3.73$3.51$3.588.35K
Aug 7, 2026$3.50$3.71$3.50$3.5719.84K
Aug 6, 2026$3.4101$3.70$3.4101$3.564.91K
Aug 5, 2026$3.50$3.69$3.3986$3.5540K
Aug 4, 2026$3.49$3.67$3.4347$3.516.37K
Aug 3, 2026$3.41$3.58$3.366$3.495.19K
Jul 31, 2026$3.48$3.595$3.3606$3.4415.71K
Jul 30, 2026$3.50$3.504$3.47$3.503.54K
Jul 29, 2026$3.46$3.5999$3.4262$3.5010.07K
Jul 28, 2026$3.50$3.655$3.37$3.5018.51K
Jul 27, 2026$3.41$3.55$3.41$3.5015.8K

Latest CYCN news

The latest Smart Investors Daily articles mentioning CYCN.

CYCN research

Overview

Company profile and research snapshot.

Company profile

Cyclerion Therapeutics Inc is a clinical-stage biopharmaceutical company harnessing the power of soluble guanylate cyclase (sGC) pharmacology to discover, develop, and commercialize breakthrough treatments for serious and orphan diseases. Its focus is on enabling the full therapeutic potential of next-generation sGC stimulators. Its pipeline products include Olinciguat, Praliciguat, and others.

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Analyst outlook

Consensus and target data currently published for this company.

Consensus
Average target
Implied upside
Analysts
CYCN recent ratings
DateFirmRatingTarget
Oct 20, 2021Truist SecuritiesBuy
Sep 24, 2021Cantor FitzgeraldOverweight
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Yahoo · Feb 23, 2026

CYCN: Positive Feedback from FDA Sets Stage for Phase 2 Trial of CYC-126 in 2H26

By David Bautz, PhD NASDAQ:CYCN READ THE FULL CYCN RESEARCH REPORT Business Update Positive Regulatory Feedback Supports Phase 2 Trial Initiation in 2H26 On February 17, 2026, Cyclerion Therapeutics, Inc. (NASDAQ:CYCN) announced that the U.S. Food and Drug Administration (FDA) provided positive written feedback to the company regarding the planned Phase 2 proof-of-concept clinical trial

Yahoo · Feb 17, 2026

Cyclerion Therapeutics Announces Progress Toward CYC-126 Phase 2 Proof-of-Concept Study with FDA Feedback and Formation of Clinical Advisory Board

–Received Positive Pre-Investigational New Drug (“IND”) Written Feedback from the U.S. Food and Drug Administration (“FDA”)– –Clinical Advisory Board (“CAB”) Includes Key Leaders across Neuropsychiatry, Anesthesiology, and Clinical Development– –Remain On Track to Initiate CYC-126's Phase 2 Proof-of-Concept (“POC”) Study in Treatment Resistant Depression (“TRD”) in the Second Half of 2026– CAMBRIDGE, Mass., Feb. 17, 2026 (GLOBE NEWSWIRE) -- Cyclerion Therapeutics, Inc. (Nasdaq: CYCN) (“Cyclerion

Yahoo · Feb 2, 2026

CYCN: Engineering a Reset; Initiating Coverage of Cyclerion Therapeutics…

By David Bautz, PhD NASDAQ:CYCN READ THE FULL CYCN RESEARCH REPORT Initiating Coverage We are initiating coverage of Cyclerion Therapeutics, Inc. (NASDAQ:CYCN) with a valuation of $8.00. Cyclerion is a clinical-stage biopharmaceutical company that has recently undergone a strategic transformation to focus on the development of novel neuropsychiatric therapies, with an initial emphasis on

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