Yahoo · Oct 23, 2026
IDE849 (SHR-4849) DLL3 TOP1 ADC Updated Phase 1 Results at ESMO 2026 Demonstrates Promising Anti-Tumor Activity and Preliminary Overall Survival Results in Relapsed Small Cell Lung Cancer and Neuroendocrine Carcinomas
IDEAYA Biosciences, Inc. (Nasdaq: IDYA) today announced updated clinical results that show promising anti-tumor activity and preliminary overall survival results for IDE849 (SHR-4849), its investigational antibody-drug conjugate (ADC) directed against delta-like ligand 3 (DLL3) and carrying a topoisomerase I (TOP1) inhibitor payload. IDEAYA's partner, Jiangsu Hengrui Pharmaceuticals Co., Ltd. (Hengrui), is presenting the results from its Phase 1 study in China in relapsed small cell lung cancer


