Benzinga · Aug 19, 2026
JP Morgan Maintains Overweight on Septerna, Raises Price Target to $48
JP Morgan analyst Tessa Romero maintains Septerna (NASDAQ:SEPN) with a Overweight and raises the price target from $38 to $48.
SE
NASDAQ · SEPN
Septerna, Inc. Common Stock
Healthcare · Biotechnology
$36.75
Down-$0.05 (-0.14%)
Updated Sep 6, 2026, 7:17 AM
SID Score
5.0/10
Composite research score
Smart Money
—
Institutional and insider signal
- Market cap
- 1.17B
- P/E ratio
- -19.76
- Dividend yield
- 0.00%
- 52-week range
- $13.67 – $51.10
- Volume
- 199.67K
- Avg. volume
- 331.52K
Price performance
SEPN price history
1M range · 20 trading sessions · Daily adjusted prices
SEPN closed at $36.75 after 20 trading sessions, down 5.41% for the selected period.
- Last close
- $36.75
- Period change
- -5.41%
- Period low
- $36.75
- Period high
- $48.19
Daily close
View OHLC price history
| Date | Open | High | Low | Close | Volume |
|---|---|---|---|---|---|
| Sep 4, 2026 | $36.57 | $37.59 | $36.57 | $36.75 | 199.67K |
| Sep 3, 2026 | $37.72 | $38.195 | $36.46 | $36.80 | 241.56K |
| Sep 2, 2026 | $37.96 | $38.86 | $37.245 | $37.50 | 263.25K |
| Sep 1, 2026 | $38.15 | $38.57 | $37.24 | $37.68 | 263.95K |
| Aug 31, 2026 | $38.71 | $39.105 | $37.39 | $38.15 | 415.35K |
| Aug 28, 2026 | $40.25 | $40.945 | $38.74 | $38.91 | 385.88K |
| Aug 27, 2026 | $40.01 | $41.08 | $39.95 | $40.47 | 266.54K |
| Aug 26, 2026 | $41.08 | $41.355 | $40.12 | $40.25 | 168.48K |
| Aug 25, 2026 | $41.57 | $41.85 | $40.47 | $41.30 | 333.38K |
| Aug 24, 2026 | $39.76 | $40.90 | $38.96 | $40.52 | 520.55K |
| Aug 21, 2026 | $41.44 | $41.44 | $39.95 | $40.00 | 289.81K |
| Aug 20, 2026 | $43.15 | $43.6192 | $40.24 | $40.79 | 430K |
| Aug 19, 2026 | $44.65 | $44.93 | $43.49 | $43.93 | 383.52K |
| Aug 18, 2026 | $43.69 | $44.58 | $43.37 | $43.80 | 332.88K |
| Aug 17, 2026 | $44.01 | $45.41 | $43.69 | $44.20 | 433.68K |
| Aug 14, 2026 | $45.00 | $46.50 | $43.64 | $44.50 | 630.37K |
| Aug 13, 2026 | $47.83 | $48.95 | $45.10 | $45.14 | 877.88K |
| Aug 12, 2026 | $47.93 | $51.10 | $47.40 | $48.19 | 1.26M |
| Aug 11, 2026 | $39.57 | $48.00 | $38.62 | $47.76 | 1.16M |
| Aug 10, 2026 | $38.56 | $39.71 | $38.0501 | $38.85 | 275.48K |
Latest SEPN news
The latest Smart Investors Daily articles mentioning SEPN.
Stock researchCompany · Overview
SEPN research
Overview
Company profile and research snapshot.
Company profile
Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, GLP-1R, GIPR, and GCGR.
Visit company websiteAnalyst outlook
Consensus and target data currently published for this company.
- Consensus
- —
- Average target
- $28.00
- Implied upside
- —
- Analysts
- —
| Date | Firm | Rating | Target |
|---|---|---|---|
| Aug 19, 2026 | JP Morgan | Overweight | — |
| Aug 13, 2026 | Jones Trading | Buy | — |
| Aug 12, 2026 | Wells Fargo | Overweight | — |
| Aug 12, 2026 | HC Wainwright & Co. | Buy | — |
| Aug 11, 2026 | Guggenheim | Buy | — |
News briefing
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Benzinga · Aug 13, 2026
Jones Trading Maintains Buy on Septerna, Raises Price Target to $62
Jones Trading analyst Catherine Novack maintains Septerna (NASDAQ:SEPN) with a Buy and raises the price target from $43 to $62.
Benzinga · Aug 12, 2026
Wells Fargo Maintains Overweight on Septerna, Raises Price Target to $50
Wells Fargo analyst Derek Archila maintains Septerna (NASDAQ:SEPN) with a Overweight and raises the price target from $48 to $50.
Benzinga · Aug 12, 2026
HC Wainwright & Co. Maintains Buy on Septerna, Raises Price Target to $60
HC Wainwright & Co. analyst Raghuram Selvaraju maintains Septerna (NASDAQ:SEPN) with a Buy and raises the price target from $40 to $60.
AI research layers
Interpretive context generated from the platform’s current data sources.
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