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Smart Investors Daily
SP

NASDAQ · SPRB

Spruce Biosciences, Inc.

Healthcare · Biotechnology

$40.40

Up+$0.83 (+2.05%)

Updated Oct 20, 2026, 11:29 PM

SID Score

2.7/10

Composite research score

Smart Money

—

Institutional and insider signal

Market cap
51.65M
P/E ratio
-1.12
Dividend yield
0.00%
52-week range
$38.06 – $159.41
Volume
57.1K
Avg. volume
571.26K

Price performance · SPRB

SPRB price history

1M range · 21 trading sessions · Daily adjusted prices

Prices through Oct 19, 2026

SPRB closed at $40.40 after 21 trading sessions, down 24.77% for the selected period.

Last close
$40.40
Period change
-24.77%
Period low
$38.98
Period high
$53.70
Daily close
View OHLC price history
SPRB OHLC price history, latest 40 sessions
DateOpenHighLowCloseVolume
Oct 19, 2026$39.97$41.00$39.2475$40.4057.1K
Oct 16, 2026$41.53$41.84$39.21$39.6588.43K
Oct 15, 2026$39.00$41.88$39.00$41.4763.78K
Oct 14, 2026$40.00$41.44$38.06$38.98113.39K
Oct 13, 2026$42.80$42.91$40.19$40.35110.8K
Oct 12, 2026$44.09$44.935$42.55$42.8774.87K
Oct 9, 2026$44.84$45.04$42.80$44.0583.76K
Oct 8, 2026$43.50$45.645$43.34$45.5450.82K
Oct 7, 2026$42.56$45.3999$42.37$44.4059.7K
Oct 6, 2026$45.60$46.72$42.50$42.785101.89K
Oct 5, 2026$45.51$46.7955$43.83$45.4265.09K
Oct 2, 2026$46.58$47.725$44.125$45.7177.24K
Oct 1, 2026$48.15$49.20$44.47$44.7779.63K
Sep 30, 2026$47.78$49.95$47.76$48.5861.26K
Sep 29, 2026$47.55$47.9999$46.55$47.2784.21K
Sep 28, 2026$48.28$48.99$47.01$47.5142.37K
Sep 25, 2026$49.22$49.31$47.54$48.7237.19K
Sep 24, 2026$49.01$49.50$47.58$49.0285.78K
Sep 23, 2026$50.50$50.735$45.01$49.415174.77K
Sep 22, 2026$54.05$54.98$49.23$49.99140.92K
Sep 21, 2026$53.84$55.055$53.07$53.7097.02K

Latest SPRB news

The latest Smart Investors Daily articles mentioning SPRB.

SPRB research

Overview

Company profile and research snapshot.

Company profile

Spruce Biosciences Inc is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with unmet medical needs. The pipeline products of the company include Tralesinidase Alfa (TA-ERT), and Tildacerfont/ Cortibon, a Companion Diagnostic, developed in partnership with HMNC Brain Health.

Visit company website

Analyst outlook

Consensus and target data currently published for this company.

Consensus
—
Average target
$209.50
Implied upside
—
Analysts
—
SPRB recent ratings
DateFirmRatingTarget
Sep 24, 2026CitizensMarket Outperform—
Sep 17, 2026Lake StreetBuy—
Aug 17, 2026GuggenheimBuy—
Aug 13, 2026CitizensMarket Outperform—
Jul 13, 2026B. Riley SecuritiesBuy—
Open full forecast

News briefing

No generated briefing is available yet.

AI research layers

Interpretive context generated from the platform’s current data sources.

No results

AI research layers have not been published yet.