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Delayed
Smart Investors Daily
SP

NASDAQ · SPRB

Spruce Biosciences, Inc.

Healthcare · Biotechnology

$47.51

Down-$1.21 (-2.48%)

Updated Sep 29, 2026, 1:00 PM

SID Score

3.6/10

Composite research score

Smart Money

—

Institutional and insider signal

Market cap
51.65M
P/E ratio
-1.12
Dividend yield
0.00%
52-week range
$7.26 – $240.00
Volume
42.37K
Avg. volume
571.26K

Price performance · SPRB

SPRB price history

1M range · 20 trading sessions · Daily adjusted prices

Prices through Sep 28, 2026

SPRB closed at $47.51 after 20 trading sessions, down 19.43% for the selected period.

Last close
$47.51
Period change
-19.43%
Period low
$47.51
Period high
$59.67
Daily close
View OHLC price history
SPRB OHLC price history, latest 40 sessions
DateOpenHighLowCloseVolume
Sep 28, 2026$48.28$48.99$47.01$47.5142.37K
Sep 25, 2026$49.22$49.31$47.54$48.7237.19K
Sep 24, 2026$49.01$49.50$47.58$49.0285.78K
Sep 23, 2026$50.50$50.735$45.01$49.415174.77K
Sep 22, 2026$54.05$54.98$49.23$49.99140.92K
Sep 21, 2026$53.84$55.055$53.07$53.7097.02K
Sep 18, 2026$53.04$53.86$51.80$53.0599.66K
Sep 17, 2026$56.22$57.105$53.28$53.86135.27K
Sep 16, 2026$55.01$56.27$53.26$54.16100.4K
Sep 15, 2026$55.99$56.36$54.51$55.165110.11K
Sep 14, 2026$53.28$57.55$52.66$56.85102.62K
Sep 11, 2026$54.78$56.08$53.09$53.7088.51K
Sep 10, 2026$55.61$57.50$54.03$54.35118.76K
Sep 9, 2026$58.52$59.01$55.7001$55.7496.36K
Sep 8, 2026$57.39$60.51$56.60$59.09193.05K
Sep 4, 2026$57.37$58.19$56.57$57.93104.95K
Sep 3, 2026$59.76$60.315$57.30$57.71116.62K
Sep 2, 2026$56.52$60.13$56.52$59.67268.14K
Sep 1, 2026$58.01$58.05$55.34$55.6058.13K
Aug 31, 2026$60.54$60.90$57.575$58.9744.94K

Latest SPRB news

The latest Smart Investors Daily articles mentioning SPRB.

SPRB research

Overview

Company profile and research snapshot.

Company profile

Spruce Biosciences Inc is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with unmet medical needs. The pipeline products of the company include Tralesinidase Alfa (TA-ERT), and Tildacerfont/ Cortibon, a Companion Diagnostic, developed in partnership with HMNC Brain Health.

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Analyst outlook

Consensus and target data currently published for this company.

Consensus
—
Average target
$209.50
Implied upside
—
Analysts
—
SPRB recent ratings
DateFirmRatingTarget
Sep 24, 2026CitizensMarket Outperform—
Sep 17, 2026Lake StreetBuy—
Aug 17, 2026GuggenheimBuy—
Aug 13, 2026CitizensMarket Outperform—
Jul 13, 2026B. Riley SecuritiesBuy—
Open full forecast

News briefing

No generated briefing is available yet.

AI research layers

Interpretive context generated from the platform’s current data sources.

No results

AI research layers have not been published yet.