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Smart Investors Daily
UP

NASDAQ · UPB

Upstream Bio, Inc.

Healthcare · Biotechnology

$4.59

Up+$0.02 (+0.44%)

Updated Oct 7, 2026, 4:23 PM

SID Score

3.2/10

Composite research score

Smart Money

—

Institutional and insider signal

Market cap
1.48B
P/E ratio
-14.14
Dividend yield
0.00%
52-week range
$4.67 – $10.67
Volume
1.06M
Avg. volume
437.05K

Price performance · UPB

UPB price history

1M range · 21 trading sessions · Daily adjusted prices

Prices through Oct 6, 2026

UPB closed at $4.59 after 21 trading sessions, down 25.85% for the selected period.

Last close
$4.59
Period change
-25.85%
Period low
$4.59
Period high
$6.19
Daily close
View OHLC price history
UPB OHLC price history, latest 40 sessions
DateOpenHighLowCloseVolume
Oct 6, 2026$4.84$4.865$4.53$4.591.06M
Oct 5, 2026$5.07$5.10$4.665$4.851.01M
Oct 2, 2026$5.12$5.21$4.86$5.04956.52K
Oct 1, 2026$5.25$5.345$4.98$5.04832.38K
Sep 30, 2026$5.23$5.455$5.145$5.27851.22K
Sep 29, 2026$5.28$5.305$4.99$5.19784.21K
Sep 28, 2026$5.34$5.385$5.12$5.30615.4K
Sep 25, 2026$5.20$5.39$5.07$5.36429.21K
Sep 24, 2026$5.19$5.20$5.045$5.17566.58K
Sep 23, 2026$5.48$5.49$4.985$5.19552.99K
Sep 22, 2026$5.44$5.56$5.38$5.49360.53K
Sep 21, 2026$5.42$5.44$5.27$5.365364.04K
Sep 18, 2026$5.32$5.41$5.21$5.341M
Sep 17, 2026$5.44$5.48$5.235$5.31533.87K
Sep 16, 2026$5.49$5.54$5.27$5.33497.24K
Sep 15, 2026$5.81$5.81$5.455$5.48421.27K
Sep 14, 2026$5.75$5.87$5.70$5.81491.02K
Sep 11, 2026$5.84$5.84$5.65$5.73501.31K
Sep 10, 2026$5.86$5.86$5.67$5.75562.41K
Sep 9, 2026$6.14$6.20$5.77$5.96726.24K
Sep 8, 2026$6.01$6.21$5.77$6.19952.24K

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