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Smart Investors Daily
AL

NYSE · ALNY

Alnylam Pharmaceuticals, Inc.

Healthcare · Biotechnology

$232.68

Up+$8.15 (+3.63%)

Updated Oct 10, 2026, 6:36 PM

SID Score

4.7/10

Composite research score

Smart Money

47/100

Neutral

Market cap
44.15B
P/E ratio
140.31
Dividend yield
0.00%
52-week range
$197.81 – $495.55
Volume
959.45K
Avg. volume
1.54M

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Latest ALNY news

The latest Smart Investors Daily articles mentioning ALNY.

ALNY research

Overview

Company profile and research snapshot.

Company profile

Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway in cells that enables sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.

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Analyst outlook

Consensus and target data currently published for this company.

Consensus
Buy
Average target
$495.36
Implied upside
—
Analysts
20
ALNY recent ratings
DateFirmRatingTarget
Oct 8, 2026RBC CapitalOutperform—
Sep 30, 2026JP MorganOverweight—
Sep 21, 2026HC Wainwright & Co.Buy—
Sep 8, 2026JefferiesHold—
Sep 2, 2026HC Wainwright & Co.Buy—
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Yahoo · Sep 29, 2026

AMVUTTRA® (vutrisiran) ‘Play by Play’ Initiative Highlights Former Athletes’ Stories to Shine a Light on the Often-Missed Signs of ATTR-CM

CAMBRIDGE, Mass., September 29, 2026--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced the launch of AMVUTTRA® (vutrisiran) ‘Play by Play,’ a U.S. educational initiative featuring former professional athletes living with the cardiomyopathy of transthyretin-mediated amyloidosis (ATTR-CM) and the care teams who support them. Through personal stories and expert perspectives, ‘Play by Play’ aims to help people recognize the symptoms of ATTR-CM earl

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