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Smart Investors Daily
CO

NASDAQ · COGT

Cogent Biosciences, Inc. Common Stock

Healthcare · Biotechnology

$32.00

Up+$0.63 (+1.97%)

Updated Sep 22, 2026, 10:52 PM

SID Score

4.6/10

Composite research score

Smart Money

58/100

Neutral

Market cap
5.7B
P/E ratio
-16.13
Dividend yield
0.00%
52-week range
$11.60 – $43.73
Volume
3.42M
Avg. volume
3.12M

Price performance

COGT price history

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Latest COGT news

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COGT research

Overview

Company profile and research snapshot.

Company profile

Cogent Biosciences Inc a biotechnology company focused on developing precision therapies for genetically defined diseases. It designs rational precision therapies that treat the underlying cause of disease and improve the lives of patients. Its program CGT9486, is a selective tyrosine kinase inhibitor designed to potently inhibit the KIT D816V mutation as well as other mutations in KIT exon 17. In the vast majority of cases, KIT D816V is responsible for driving Systemic Mastocytosis (SM), a serious disease caused by the unchecked proliferation of mast cells. Exon 17 mutations are also found in patients with advanced gastrointestinal stromal tumors (GIST), a type of cancer with dependence on oncogenic KIT signaling.

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Analyst outlook

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Consensus
Average target
$41.20
Implied upside
Analysts
COGT recent ratings
DateFirmRatingTarget
Sep 16, 2026WedbushOutperform
Sep 15, 2026HC Wainwright & Co.Buy
Aug 17, 2026Piper SandlerOverweight
Aug 12, 2026GuggenheimBuy
May 29, 2026WedbushOutperform
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Yahoo · Sep 15, 2026

Cogent Biosciences Announces FDA Acceptance of New Drug Application (NDA) for Bezuclastinib in Patients with Advanced Systemic Mastocytosis (AdvSM)

NDA supported by positive results from the APEX pivotal trial demonstrating clinically meaningful responses and evidence of disease modification in patients with AdvSM PDUFA target action date set for June 29, 2027 WALTHAM, Mass. and BOULDER, Colo., Sept. 15, 2026 (GLOBE NEWSWIRE) -- Cogent Biosciences, Inc. (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetically defined diseases, today announced that the U.S. Food and Drug Administration (FDA) has accep

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