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Smart Investors Daily
DN

NASDAQ · DNLI

Denali Therapeutics Inc.

Healthcare · Biotechnology

$24.92

Down-$0.03 (-0.12%)

Updated Aug 22, 2026, 9:00 AM

SID Score

6.8/10

Composite research score

Smart Money

Institutional and insider signal

Market cap
2.55B
P/E ratio
-6
Dividend yield
0.00%
52-week range
$12.58 – $27.30
Volume
680.99K
Avg. volume
1.72M

Price performance

DNLI price history

1M range · 21 trading sessions · Daily adjusted prices

DNLI closed at $24.92 after 21 trading sessions, up 7.83% for the selected period.

Last close
$24.92
Period change
+7.83%
Period low
$23.02
Period high
$25.69
Daily close
View OHLC price history
DNLI OHLC price history, latest 40 sessions
DateOpenHighLowCloseVolume
Aug 21, 2026$25.25$25.37$24.60$24.92680.99K
Aug 20, 2026$25.15$25.6031$24.65$24.95976.85K
Aug 19, 2026$25.00$25.70$24.61$25.691.15M
Aug 18, 2026$24.17$24.49$24.01$24.311.1M
Aug 17, 2026$24.29$24.66$24.11$24.351M
Aug 14, 2026$24.53$24.62$24.115$24.40890K
Aug 13, 2026$25.24$25.64$24.81$24.821.35M
Aug 12, 2026$24.51$25.34$24.20$25.271.44M
Aug 11, 2026$25.07$25.29$24.59$24.691.15M
Aug 10, 2026$24.71$25.035$24.21$25.001.56M
Aug 7, 2026$25.41$25.74$24.235$24.831.75M
Aug 6, 2026$24.48$24.99$24.37$24.733.05M
Aug 5, 2026$24.29$24.55$23.96$24.421.09M
Aug 4, 2026$23.55$24.30$23.23$24.17993.77K
Aug 3, 2026$22.85$23.50$22.6275$23.151.48M
Jul 31, 2026$24.34$24.35$22.99$23.021.23M
Jul 30, 2026$23.83$24.68$23.785$24.351.12M
Jul 29, 2026$24.20$24.3864$23.61$23.851.38M
Jul 28, 2026$23.92$24.055$23.15$24.052.11M
Jul 27, 2026$23.59$24.17$23.44$23.571.75M
Jul 24, 2026$23.52$23.65$22.64$23.111.16M

Latest DNLI news

The latest Smart Investors Daily articles mentioning DNLI.

DNLI research

Overview

Company profile and research snapshot.

Company profile

Denali Therapeutics Inc is a biotechnology company that is engaged in developing and discovering therapeutics to defeat neurodegeneration disease. The company's development programs include the LRRK2 Inhibitor Program, which develops brain penetrant small molecule LRRK2 inhibitor product candidates for Parkinson's disease. Its key products include DNL201, DNL151, DNL747, ATV (Antibody Transport Vehicle), ETV (Enzyme Transport Vehicle), and others.

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Analyst outlook

Consensus and target data currently published for this company.

Consensus
Average target
$33.50
Implied upside
Analysts
DNLI recent ratings
DateFirmRatingTarget
Aug 7, 2026UBSBuy
Jul 23, 2026Morgan StanleyOverweight
Jul 16, 2026Deutsche BankBuy
Jul 13, 2026JP MorganOverweight
May 26, 2026Morgan StanleyOverweight
Open full forecast

News briefing

No generated briefing is available yet.

Yahoo · Feb 26, 2026

Denali Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Business Highlights

Tividenofusp alfa (DNL310; ETV:IDS) launch readiness established ahead of April 5, 2026 Prescription Drug User Fee Act (PDUFA) target action date for Hunter syndromeDNL126 (ETV:SGSH) Phase 1/2 preliminary data presented at 2026 WORLDSymposium™, supporting plans to pursue an accelerated approval path in Sanfilippo syndrome type AStart-up activities underway for DNL628 (OTV:MAPT) Phase 1b study for Alzheimer's disease and DNL952 (ETV:GAA) Phase 1 study for late-onset Pompe diseaseTransportVehicle™

AI research layers

Interpretive context generated from the platform’s current data sources.

No results

AI research layers have not been published yet.