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Smart Investors Daily
PR

NASDAQ · PRME

Prime Medicine, Inc.

Healthcare · Biotechnology

$3.50

Up+$0.40 (+11.43%)

Updated Oct 7, 2026, 8:45 PM

SID Score

4.0/10

Composite research score

Smart Money

—

Institutional and insider signal

Market cap
754.01M
P/E ratio
-3.46
Dividend yield
0.00%
52-week range
$2.67 – $4.83
Volume
12.02M
Avg. volume
3.98M

Price performance · PRME

PRME price history

1M range · 21 trading sessions · Daily adjusted prices

Prices through Oct 6, 2026

PRME closed at $3.50 after 21 trading sessions, down 1.69% for the selected period.

Last close
$3.50
Period change
-1.69%
Period low
$2.88
Period high
$3.56
Daily close
View OHLC price history
PRME OHLC price history, latest 40 sessions
DateOpenHighLowCloseVolume
Oct 6, 2026$3.56$3.7176$3.26$3.5012.02M
Oct 5, 2026$3.00$3.26$2.88$3.214.72M
Oct 2, 2026$3.05$3.075$2.92$2.982.11M
Oct 1, 2026$3.05$3.105$2.98$2.992.83M
Sep 30, 2026$3.11$3.19$3.02$3.0553.13M
Sep 29, 2026$2.93$3.135$2.88$3.093.61M
Sep 28, 2026$2.85$2.92$2.77$2.8753.68M
Sep 25, 2026$3.42$3.44$2.875$2.907.12M
Sep 24, 2026$3.11$3.13$2.9901$3.074.49M
Sep 23, 2026$3.53$3.53$3.12$3.133.33M
Sep 22, 2026$3.22$3.565$3.20$3.542.73M
Sep 21, 2026$3.19$3.27$3.10$3.192.95M
Sep 18, 2026$3.13$3.17$3.045$3.124.67M
Sep 17, 2026$3.11$3.39$3.10$3.143.25M
Sep 16, 2026$3.18$3.22$2.93$3.003.29M
Sep 15, 2026$3.18$3.22$3.00$3.142.57M
Sep 14, 2026$3.10$3.28$3.10$3.181.62M
Sep 11, 2026$3.38$3.44$3.10$3.133.08M
Sep 10, 2026$3.37$3.42$3.31$3.352.39M
Sep 9, 2026$3.47$3.535$3.29$3.474.23M
Sep 8, 2026$3.65$3.65$3.41$3.563.6M

Latest PRME news

The latest Smart Investors Daily articles mentioning PRME.

PRME research

Overview

Company profile and research snapshot.

Company profile

Prime Medicine Inc is a biotechnology company committed to delivering genetic therapies to address diseases by deploying gene editing technology, Prime Editing. The Prime Editing technology is a next-generation technology that can search and replace to restore normal genetic function in the genome and can treat a wide spectrum of diseases with high unmet medical needs and efficient and broad gene editing technology.

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Analyst outlook

Consensus and target data currently published for this company.

Consensus
Buy
Average target
$17.25
Implied upside
—
Analysts
17
PRME recent ratings
DateFirmRatingTarget
Sep 25, 2026Chardan CapitalBuy—
Aug 25, 2026Chardan CapitalBuy—
Aug 19, 2026BMO CapitalOutperform—
Aug 10, 2026HC Wainwright & Co.Buy—
Jun 29, 2026HC Wainwright & Co.Buy—
Open full forecast

News briefing

Generated Oct 7, 2026, 9:12 PM

Why Is PRME Up 11.43% Today?

Prime Medicine shares surged 11.43% on news that the company has dosed its first patient in a global Phase 1/2 clinical trial for PM577a, a treatment targeting H1069Q-mutated Wilson Disease. This clinical milestone represents a significant step forward in the company's gene editing pipeline and has energized investor sentiment around its therapeutic approach.

    Bottom line: Prime Medicine's first patient dosing in the PM577a trial is a legitimate clinical milestone that justifies near-term investor enthusiasm, evidenced by today's 11.43% gain. However, investors should recognize this as an early-stage development event; clinical validation is still many quarters away, and gene therapy execution risks remain material. Watch for Phase 1/2 safety and preliminary efficacy data as the critical near-term catalyst.

    Yahoo · Oct 5, 2026

    Prime Medicine Announces First Patient Dosed in Global Phase 1/2 Clinical Trial of PM577a for H1069Q-Mutated Wilson Disease

    -- Global, first-in-human study underway designed to evaluate safety, tolerability, and initial clinical efficacy of PM577a -- -- PM577a is designed as a one-time therapy to correct the H1069Q mutation in ATP7B, the most prevalent Wilson disease-causing mutation in North America and Europe‌ -- -- PM577 granted Rare Pediatric Disease Designation by the U.S. FDA -- -- Initial clinical data expected in 2027 -- CAMBRIDGE, Mass., Oct. 05, 2026 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (Nasdaq: PRME),

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