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Smart Investors Daily
SG

NASDAQ · SGMT

Sagimet Biosciences Inc.

Healthcare · Biotechnology

$8.88

Up+$0.12 (+1.37%)

Updated Oct 8, 2026, 2:16 AM

SID Score

5.0/10

Composite research score

Smart Money

—

Institutional and insider signal

Market cap
196.86M
P/E ratio
-3.57
Dividend yield
0.00%
52-week range
$4.50 – $11.45
Volume
631.65K
Avg. volume
561.82K

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Overview

Company profile and research snapshot.

Company profile

Sagimet Biosciences Inc is a clinical-stage biopharmaceutical company dedicated to developing a portfolio of in-house discovered, selective fatty acid synthase (FASN) inhibitors aimed at treating diseases that arise from dysfunctional lipid metabolism pathways. The company's drug candidate, denifanstat, is an oral, once-daily pill that serves as a selective FASN inhibitor under development for treating nonalcoholic steatohepatitis (NASH). The company functions as a single business segment, focusing on the development and commercialization of therapeutics for MASH and other diseases where FASN plays a pathogenic role.

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Analyst outlook

Consensus and target data currently published for this company.

Consensus
Buy
Average target
$6.00
Implied upside
—
Analysts
16
SGMT recent ratings
DateFirmRatingTarget
Oct 5, 2026HC Wainwright & Co.Buy—
Oct 2, 2026GuggenheimBuy—
Oct 1, 2026OppenheimerOutperform—
Oct 1, 2026CitizensMarket Outperform—
Sep 24, 2026Goldman SachsSell—
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Yahoo · Sep 30, 2026

Sagimet Biosciences Shares Rise 12% After Denifanstat Phase 3 Acne Trial Data

Sagimet Biosciences Inc Series A (NASDAQ:SGMT) shares rose more than 12% in pre-market trading on Wednesday following the release of 52-week results from license partner Ascletis’ Phase 3 open-label extension trial evaluating denifanstat in patients with moderate to severe acne. The trial reported a 57% treatment success rate after 52 weeks of denifanstat treatment, alongside a 72% reduction in total lesions and a 77% reduction in inflammatory lesions.

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