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Smart Investors Daily
XL

NASDAQ · XLO

Xilio Therapeutics, Inc.

Healthcare · Biotechnology

$7.31

Down-$0.26 (-3.43%)

Updated Oct 27, 2026, 9:47 AM

SID Score

3.2/10

Composite research score

Smart Money

—

Institutional and insider signal

Market cap
37.56M
P/E ratio
-2.44
Dividend yield
0.00%
52-week range
$6.47 – $12.58
Volume
33.45K
Avg. volume
620.67K

Price performance · XLO

XLO price history

1M range · 21 trading sessions · Daily adjusted prices

Prices through Oct 26, 2026

XLO closed at $7.31 after 21 trading sessions, down 19.23% for the selected period.

Last close
$7.31
Period change
-19.23%
Period low
$7.31
Period high
$9.22
Daily close
View OHLC price history
XLO OHLC price history, latest 40 sessions
DateOpenHighLowCloseVolume
Oct 26, 2026$7.54$8.6368$7.05$7.3133.45K
Oct 23, 2026$8.06$8.245$7.51$7.5716.25K
Oct 22, 2026$8.45$8.48$8.00$8.0315.37K
Oct 21, 2026$8.545$9.05$8.2487$8.4336.27K
Oct 20, 2026$8.25$8.84$8.25$8.5413.51K
Oct 19, 2026$8.69$8.735$8.33$8.3311.49K
Oct 16, 2026$8.91$9.00$8.55$8.5529.6K
Oct 15, 2026$8.88$9.38$8.88$9.0210.39K
Oct 14, 2026$9.08$9.08$8.772$8.9012.42K
Oct 13, 2026$9.05$9.22$8.855$9.2218.15K
Oct 12, 2026$9.11$9.42$8.9815$9.0758.39K
Oct 9, 2026$8.94$9.16$8.82$9.055.53K
Oct 8, 2026$9.01$9.14$8.775$9.0120.79K
Oct 7, 2026$9.00$9.01$9.00$9.01885.71
Oct 6, 2026$9.10$9.32$8.81$9.006.2K
Oct 5, 2026$9.07$9.49$9.07$9.117.16K
Oct 2, 2026$8.89$9.075$8.89$9.017.4K
Oct 1, 2026$8.97$9.12$8.79$8.9112.89K
Sep 30, 2026$9.19$9.25$9.05$9.055.38K
Sep 29, 2026$9.5677$9.5677$8.9378$8.93783.11K
Sep 28, 2026$9.21$9.22$8.96$9.0511.13K

Latest XLO news

The latest Smart Investors Daily articles mentioning XLO.

XLO research

Overview

Company profile and research snapshot.

Company profile

Xilio Therapeutics Inc is a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology (I-O) therapies with the goal of significantly improving outcomes for people living with cancer without the systemic side effects of current I-O treatments. The company is using its proprietary platform to advance a pipeline of novel, tumor-activated clinical and preclinical I-O molecules that are designed to optimize the therapeutic index by localizing anti-tumor activity within the tumor microenvironment, including tumor-activated cytokines and antibodies and immune cell engagers.

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Analyst outlook

Consensus and target data currently published for this company.

Consensus
Buy
Average target
$7.00
Implied upside
—
Analysts
6
XLO recent ratings
DateFirmRatingTarget
Oct 21, 2026Raymond JamesOutperform—
Aug 6, 2025Leerink PartnersOutperform—
Nov 8, 2024Raymond JamesOutperform—
May 30, 2023Chardan CapitalBuy—
May 11, 2023Chardan CapitalBuy—
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News briefing

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Yahoo · Oct 2, 2026

Xilio Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

WALTHAM, Mass., Oct. 02, 2026 (GLOBE NEWSWIRE) -- Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing masked immuno-oncology therapies for people living with cancer, today announced that, effective October 1, 2026, the company granted non-qualified stock options to purchase an aggregate of 100,895 shares of its common stock to two new employees under Xilio Therapeutics’ Third Amended and Restated 2022 Inducement Stock Incentive Plan (the 2022

Yahoo · Sep 28, 2026

Xilio Therapeutics Appoints Yariv J. Houvras, M.D., Ph.D. as Chief Medical Officer

Dr. Houvras brings over two decades of executive leadership across premier industry and academic research institutions in clinical development, translational medicine and immuno-oncologyWALTHAM, Mass., Sept. 28, 2026 (GLOBE NEWSWIRE) -- Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing masked immuno-oncology therapies for people living with cancer, today announced the appointment of Dr. Yariv Houvras as chief medical officer. “We are thrill

Yahoo · Sep 2, 2026

Xilio Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

WALTHAM, Mass., Sept. 02, 2026 (GLOBE NEWSWIRE) -- Xilio Therapeutics, Inc. (Nasdaq: XLO), a clinical-stage biotechnology company discovering and developing masked immuno-oncology therapies for people living with cancer, today announced that, effective September 1, 2026, the company granted non-qualified stock options to purchase 19,865 shares of its common stock to two new employees under Xilio Therapeutics’ 2022 Inducement Stock Incentive Plan. The stock options have an exercise price of $8.88

AI research layers

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